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[–][deleted] 1 insightful - 1 fun1 insightful - 0 fun2 insightful - 1 fun -  (1 child)

for cross sex hormones, you need to know where the psychological gender is going to lie

Alright so it's okay to give cross-sex hormones to a child as long as you know "where the psychological gender is going to lie". What exactly is a "psychological gender" and how do you determine "where it lies"?

Puberty blockers allow the decision to be delayed until the diagnosis is certain. Many cases of gender dysphoria resolve on their own, and transitioning should be avoided until it's clear that it has to be treated.

Most cases of gender dysphoria resolve themselves unless the child is given puberty blockers, in which case the vast majority of them go on to fully medically transition.

(Bone density loss is not reversible.)[https://www.statnews.com/2017/02/02/lupron-puberty-children-health-problems/]

("Androgen deprivation therapy (Lupron/Zoladex) is associated with: 1) erectile dysfunction smooth muscle dysfunction and /or erectile tissue fibrosis damage which leads to venous leakage, 2) hypoactive sexual desire disorder which means no libido/interest and 3) orgasmic dysfunction.")[https://www.bumc.bu.edu/sexualmedicine/informationsessions/restoring-sexual-function-after-luproncancer-treatment/]

Adults who take lupron report cognitive dysfunction and show an increased risk of Alzheimer's.

I'll be here when a study comes out comparing it to a control group which proves it's safe. GnRH analogues are serious drugs and they're being used off-label. Wake me up when the FDA approves them for this use, and then we can talk more about the suffering that people who used it when it was actually approved.

The fact that you say it's reversible with no side effects is laughable because the data says otherwise for all other use-cases, and there is no long-term data for this specific use-case, nor were there ever even any clinical trials.

[–]ActuallyNot 1 insightful - 1 fun1 insightful - 0 fun2 insightful - 1 fun -  (0 children)

What exactly is a "psychological gender" and how do you determine "where it lies"?

I'm taking about whether the gender dysphoria will resolve on it's own, or whether there's something that you need to treat.

When you know that the gender dysphoria will worsen, you treat it. Otherwise you don't.

In the case of intersex kids, there's less literature, and it's not my field, but it's likely that they principles apply. You need them to get to a stage in the development that you can make a decent guess as to what's going to make for the best quality of life going forwards.

I don't mean "psychological gender" as a technical term. I just mean what is the best fit for their brain.

Bone density loss is not reversible.

That's right. Puberty blockers have side effects with negative consequences. As do most medicines.

GnRH analogues are serious drugs and they're being used off-label.

Are they?

In terms of dosage, treatment period or indication?

Jumping straight to hormones also has its risks. A lot of kids' GD resolves. There's a lot of concern about getting it right, and it's valid.

The fact that you say it's reversible

This is one of those "alternative facts" that drives conservatives' point of view in the US.

What I said was that they allow the decision to be delayed until the diagnosis is certain.