The Most Common Pain Relief Drug in The World Induces Risky Behaviour and Cognitive Decline, Study Suggests

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[–]hennojisan 7 insightful - 3 fun7 insightful - 2 fun8 insightful - 3 fun -  (9 children)

It's also liver-toxic at 1.5 grams. Since it often comes in 500 mg doses, it's easy to go over the line.

[–][deleted] 7 insightful - 3 fun7 insightful - 2 fun8 insightful - 3 fun -  (8 children)

And that liver toxicity makes it one of the most dangerous drugs out there.

acetaminophen-associated overdoses account for about 50,000 emergency room visits and 25,000 hospitalizations yearly. Acetaminophen is the nation's leading cause of acute liver failure, according to data from an ongoing study funded by the National Institutes for Health. Analysis of national mortality files shows about 450 deaths occur each year from acetaminophen-associated overdoses; 100 of these are unintentional." source

[–]JasonCarswell 2 insightful - 2 fun2 insightful - 1 fun3 insightful - 2 fun -  (0 children)

Thanks!

[–]shariajustice 2 insightful - 1 fun2 insightful - 0 fun3 insightful - 1 fun -  (6 children)

i had read before that some suicide by eating tylenol and that it causes irreversible damage to the liver.

i just read that 10 grams is fatal.. is this true? how unpleasant is the death from this and how long does it take typically?

if one were to take ten grams of tylenol, how long before it is irreversible to cause death?

[–]Trajan 1 insightful - 1 fun1 insightful - 0 fun2 insightful - 1 fun -  (4 children)

For a person of normal weight and health they'd be chewing their way through many more tablets than a person would ordinarily take (probably upwards of 20 standard). The actual fatal dose varies a fair bit. It is a deeply unpleasant way to go. With a large enough dose, considering weight and general health, your liver would begin to fail. A person in this situation would linger on for days in serious pain before they die.

[–]shariajustice 2 insightful - 1 fun2 insightful - 0 fun3 insightful - 1 fun -  (3 children)

so, if a person were to consume 25 grams(50x500mg) per day, perhaps for five days.. how long do you estimate before we are at the point of no return? how long before we are at a place where no hospital could save you?

curious minds need to know.

my true preference would have been to be eaten alive by cannibals, but i dont know any cannibals.

can you imagine being chained to a table top, they cut off my leg and toss it in the oven.. mozart is playing.. i am screaming my brains out.. and they all sit down at the table where i am chained down..

will you pass the carrots, please, someone calls out..

[–]Trajan 1 insightful - 1 fun1 insightful - 0 fun2 insightful - 1 fun -  (2 children)

I’m no expert. I looked at a few sources, like the BMJ, and it seems to vary.

I’d also choose the cannibals.

[–]shariajustice 1 insightful - 1 fun1 insightful - 0 fun2 insightful - 1 fun -  (1 child)

well, i am off to walmart to get a case of tylenol.. if you hear some screaming in the next few days, it is probably me dying from liver damage.

all love.

[–]Trajan 1 insightful - 1 fun1 insightful - 0 fun2 insightful - 1 fun -  (0 children)

I’d hold out for the cannibals. COVID travel restrictions should ease in a few months if we’re lucky.

[–][deleted] 1 insightful - 1 fun1 insightful - 0 fun2 insightful - 1 fun -  (0 children)

Howdy fellow Houstonian. It depends on the person, people just react differently to drugs (why they give fatal dosages as LD50s, the lethal dose when 50% of the subjects die), and if they catch it in time. I don't know how long it takes before it's irreversible.

I had taken too much myself back when I first injured my knee but my couch guy and wife took me to the hospital and they got lived protecterants into me right away so there was no damage. I had no idea at the time I couldn't eat them like candy, luckily they knew.

Most of my experience with liver damage comes from a couple alcoholic buds. One of them, drunken_otter on reddit, didn't have any symptoms until a month before her death. She got bloated, ascites, and constipated, and she didn't complain but it didn't sound pleasant. The other one is currently in stage 4 chirrossis and she's complained about the pain a number of times but she's been hanging on for a while now. I wouldn't pick it as a way to go.