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[–]lefterfield 9 insightful - 1 fun9 insightful - 0 fun10 insightful - 1 fun -  (7 children)

...Are you serious right now? Hormones do not work the same in male bodies as they do in female bodies, REGARDLESS of what type of hormones they are or if you are taking them at a comparable rate. TIMs interactions with estrogen can only tell us how males respond to estrogen. It tells us NOTHING about post-menopausal women.

Site your evidence that hormones literally remake physiology, and I'll dig up some studies that say that men remain men and have male symptoms - even after taking estrogen.

[–]RationalNeutral 1 insightful - 1 fun1 insightful - 0 fun2 insightful - 1 fun -  (6 children)

Something that might be useful for your search would be cross-sex heart transplants: https://www.reuters.com/article/us-heart-transplant-idUKTRE4AB7FK20081112

I would suspect that if your claim holds as much as you propose, that a cross-sex heart transplant would fail 100% of the time, but the above article is showing a 15% failure rate for men-only. Which, suggests there is something more complicated going on.

Transgender medical research MIGHT help shed light on the nuances that can decrease that kind of risk.

The article points out that Male hearts vary in size from Women's hearts, which, could be exactly influenced by sex hormones (and not genetic makeup) during puberty.

So then the question might get posed do we see the same kind of rate of failures for pre-puberty heart transplants?

That's your rabbit hole to go down though, seeing as at the moment I'm attempting to prove your point for you on the suspicion you aren't going to put in the effort.

[–]lefterfield 1 insightful - 1 fun1 insightful - 0 fun2 insightful - 1 fun -  (5 children)

I'm sorry, what? That doesn't in any way contradict anything I said. No, I would find it a far more surprising result if cross-sex transplants were always a failure. A male heart is - as far as I'm aware - very similar to a female heart, just larger. Same as a male liver, or pancreas, or kidney. Separating people into individual organs doesn't answer the question of male vs female physiology.

[–]RationalNeutral 1 insightful - 1 fun1 insightful - 0 fun2 insightful - 1 fun -  (4 children)

I'm attempting to prove your point for you on the suspicion you aren't going to put in the effort.

I literally said that I wasn't attempting to contradict you with this comment, do you even read the comments your respond to?

A male heart is - as far as I'm aware - very similar to a female heart, just larger.

So then, in the absence of larger discrepancies, like the explicit existence or nonexistence of an organ, as a whole the biochemical response (for the administration of medicine) is going to be far more similar to the sex hormone being taken at the time, correct?

[–]lefterfield 1 insightful - 1 fun1 insightful - 0 fun2 insightful - 1 fun -  (3 children)

is going to be far more similar to the sex hormone being taken at the time, correct?

Nooooo. This is the thing you need to find evidence for. Our bodies are not just organs held together by hormones.

[–]RationalNeutral 1 insightful - 1 fun1 insightful - 0 fun2 insightful - 1 fun -  (2 children)

That would more or less require me to summarize an entire medical school curriculum in a saidit comment, for that level of explanation you would be better off taking formal courses.

[–]lefterfield 2 insightful - 1 fun2 insightful - 0 fun3 insightful - 1 fun -  (1 child)

Lol. Get your head out of your ass - though check for prostate cancer before you do - and come back with an actual argument. Actually no, just leave.

[–]RationalNeutral 1 insightful - 1 fun1 insightful - 0 fun2 insightful - 1 fun -  (0 children)

I provided sources for you to do your own research, it's up to you to actually do that research though.