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[–]MarkTwainiac 6 insightful - 1 fun6 insightful - 0 fun7 insightful - 1 fun -  (0 children)

Although it's unkind to refer to them as such, such people are defects or abnormalities.

It's possible to be factual without being insulting.

I'd prefer to say that such people are anomalies. They might have developmental defects, genetic and hormonal abnormalities and other medical conditions that set them apart from "the norm" - but such people are not themselves defects or abnormalities.