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[–]Hematomato 2 insightful - 1 fun2 insightful - 0 fun3 insightful - 1 fun -  (4 children)

And the medical industry abhors a cure, but even more so any treatment that can be obtained outside of their ecosystem. Anyone can draw blood from a kid or teenager, do a simple blood type test, and infuse themselves. Anyone can open a clinic that does it professionally and ethically using volunteers.

Here's the problem, though: the Hayflick Limit works both ways. Every time you get a transfusion of young blood, you gain maybe, say, ten days of life expectancy. But every time you give a blood transfusion, your telomeres shorten as the cells replace your blood, and you lose maybe, say, fifteen days of life expectancy.

[–]Canbot 2 insightful - 1 fun2 insightful - 0 fun3 insightful - 1 fun -  (3 children)

I think you know that is wild speculation. The blood is constantly getting replaced whether or not it has been extracted and used elsewhere. There are other ways of extending telomeres. The reason this therapy is suppressed has nothing to do with an honest assessment of the pros and the cons, or a valid ethical barrier. If anything it is unethical to not support it.

[–]Hematomato 1 insightful - 1 fun1 insightful - 0 fun2 insightful - 1 fun -  (2 children)

It's not wild speculation. This is what I did for ten years of my life. Our blood gets replaced through cell division. Human cells can only divide about 50 times. Every time they divide, their telomeres get shorter. And that is the reason we age.

So, if you do something to encourage rapid and recurring cell division (like repeated blood draws), you increase the rate of aging. It's pretty much that simple.

There are other ways of extending telomeres.

The particular article you linked to is a method that works in vitro but would never work in vivo.

That said, yes, there are other ways of extending telomeres - and currently, the most promising one is mRNA tech. My company spent six years looking for a drug that would fully de-repress telomerase. Honestly, I don't think it exists. But mRNA tech would almost certainly work.

Frankly, I think there's a very realistic chance that it's as simple as: take the COVID vaccine, swap out the COVID spike protein for hTERT, and you have the cure for aging. No need to suck the blood out of children ever again!

[–]Canbot 1 insightful - 1 fun1 insightful - 0 fun2 insightful - 1 fun -  (1 child)

Red blood cells do not come from the division of other red blood cells, they are produced in the bone marrow from stem cells.

It's not wild speculation.

Then perhaps you can direct me to the study that has measured the effects on blood draws on life expectancy down to the week.

[–]Hematomato 1 insightful - 1 fun1 insightful - 0 fun2 insightful - 1 fun -  (0 children)

Red blood cells aren't part of the immune system. We're talking about the white ones. The immune system ages and senesces through cell division, and that's the one of the main drivers of our life expectancy. We have a programmed death at no more than 125 years of age, as our immune system senesces and becomes unable to clean up cancers the way it used to. Adding a young immune system into our veins is a way to partially cheat that limit.

Then perhaps you can direct me to the study that has measured the effects on blood draws on life expectancy down to the week.

It's impossible; we don't have the technology to measure anything down to the week. So we have no idea what the real numbers are (which is why I said "maybe, say,").

But we do know that there are numbers - repeated blood transfusions from young to old will increase the life expectancy of the old while reducing the life expectancy of the young.