"If you want to understand a society, take a good look at the drugs it uses. And what can this tell you about American culture? Well, look at the drugs we use. Except for pharmaceutical poison, there are essentially only two drugs that Western civilization tolerates:...

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It seems to be a part of US "ideology" that for every symptom or problem, there is a corresponding pill to "cure" it. Even when it isn't even a treatment, but only an FDA-approval for this drug in this context in question. Which is the result of politics behind closed doors, bribes switching hands, certainly not a rather "scientific" entitled process.

Without this mindset, the opioid crisis possibly couldn't have been possible.

Above that: Prescription drugs seem to be regarded as rather harmless for most parts by the public. This isn't any better in Germany, though.

Which then bites their users in their asses when they start to combine different drugs.

The quoted numbers I regard as rather lower bounds for gen pop in the US. Maybe even the world in general, where this kind of drugs are available, from my experience.