Ibuprofen will wreck your stomach lining if you take too much, and you can't alternate it with naproxen like you can with acetaminophen/paracetamol during high fevers. If you use them infrequently, you should be relatively fine unless you have conditions that could end up exacerbated by it, or are taking a medication/supplement with it that alters the way that you absorb or filter it out.