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[–]GConly 18 insightful - 2 fun18 insightful - 1 fun19 insightful - 2 fun -  (7 children)

When the experiment was designed, the GIDS had a caseload of only 29 teenagers aged between 12 and 15 (Viner et al., 2010, pp. 8–9), and so they planned to enrol 30–45 patients over three years. Referrals subsequently grew exponentially, perhaps helped by Dr Carmichael’s promotion of puberty blockers in newspaper interviews and on BBC Children’s Television.

So they were not getting enough guinea pigs, so they recruited them?

I'm also not seeing any research into the effect on IQ, which is a known side effect of blockers.

[–]reluctant_commenter[S] 11 insightful - 1 fun11 insightful - 0 fun12 insightful - 1 fun -  (6 children)

I'm also not seeing any research into the effect on IQ, which is a known side effect of blockers.

That's fascinating, I've never heard of that. Do you know of any studies about it? I found this case study wherein the participant's operational memory dropped by 9 points (that's kind of big). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5694455/

[–]GConly 12 insightful - 1 fun12 insightful - 0 fun13 insightful - 1 fun -  (1 child)

Yes, there's a few but they might take me a while to find on my old Reddit account.

IIRC: there's a couple in girls with precocious puberty that showed a big drop.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5253377/

It was found that the girls had a mean IQ of 94, as against a mean IQ of 102 for the matched control group

So an eight point difference.

I've seen a study in adults using it for other reasons and it showed it damaged a particular area of the brain involved with memory, but I'm buggered if I can locate the paper.

I'll give it my best and see what I can find overnight.

[–]reluctant_commenter[S] 8 insightful - 1 fun8 insightful - 0 fun9 insightful - 1 fun -  (0 children)

Awesome, thank you so much! That alone is helpful.