all 6 comments

[–]IkeConn 5 insightful - 1 fun5 insightful - 0 fun6 insightful - 1 fun -  (0 children)

Trump should have never mentioned it. Just because he said the word "Ivermectin" the deep state has demonized it.

[–][deleted] 5 insightful - 1 fun5 insightful - 0 fun6 insightful - 1 fun -  (2 children)

My cats had really persistent pinworms. Squirming worms coming out of your ass is super noticeable (and gross). I don't think that's likely to be the silent affliction ivermectin is curing.

This author just doesn't understand pharmacology. Ivermectin's anti- parasitical effects and anti-viral properties are incidental.

Ivermectin has exhibited antiviral activity against a wide range of RNA and some DNA viruses, for example, Zika, dengue, yellow fever, and others.13 Caly et al14 demonstrated specific action against SARS-CoV-2 in vitro with a suggested host-directed mechanism of action being the blocking of the nuclear import of viral proteins14,15 that suppress normal immune responses. However, the necessary cell culture EC50 may not be achievable in vivo.16 Other conjectured mechanisms include inhibition of SARS-CoV-2 3CLPro activity17,18 (a protease essential for viral replication), a variety of anti-inflammatory effects,19 and competitive binding of ivermectin with the viral S protein as shown in multiple in silico studies.20 The latter would inhibit viral binding to ACE-2 receptors suppressing infection. Hemagglutination via viral binding to sialic acid receptors on erythrocytes is a recently proposed pathologic mechanism21 that would be similarly disrupted. Both host-directed and virus-directed mechanisms have thus been proposed, the clinical mechanism may be multimodal, possibly dependent on disease stage, and a comprehensive review of mechanisms of action is warranted. https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC8248252/

Here's why it works on parasites:

Ivermectin and its related drugs act by interfering with the nerve and muscle functions of helminths and insects.[74] The drug binds to glutamate-gated chloride channels common to invertebrate nerve and muscle cells.[75] The binding pushes the channels open, which increases the flow of chloride ions and hyper-polarizes the cell membranes,[74] paralyzing and killing the invertebrate.[75] https://en.wikipedia.org/wiki/Ivermectin

[–]Melodic_Programmer 2 insightful - 1 fun2 insightful - 0 fun3 insightful - 1 fun -  (1 child)

Some people do believe in regular deworming with herbs to maintain good health, parasites aren't necessarily always squirming out of your ass (that felt very gross to type). But yeah, ivermectin is useful against viruses.

[–][deleted] 2 insightful - 1 fun2 insightful - 0 fun3 insightful - 1 fun -  (0 children)

Some people believe in squirting bleach up their assholes to kill parasites. Some people believe their children have autism/whatever bc of parasites and squirt bleach up their assholes. The stringy stuff that comes out, that they think are dead parasites, are intestinal lining. Due to IBS I know exactly what that's like. It does look worm like. But this is damaging tissue with bleach... Although bleach actually has really interesting regenerative properties on tissue, it isn't supposed to be full strength....

[–]Infoloop[S] 2 insightful - 2 fun2 insightful - 1 fun3 insightful - 2 fun -  (0 children)

https://en.wikipedia.org/wiki/Pinworm_infection

Pinworm infection (threadworm infection in the UK), also known as enterobiasis, is a human parasitic disease caused by the pinworm.[3] The most common symptom is itching in the anal area.[1] This can make sleeping difficult.[1] The period of time from swallowing eggs to the appearance of new eggs around the anus is 4 to 8 weeks.[2] Some people who are infected do not have symptoms.[1]

The Author in my book is not trying to be a scientist but has a conjecture, an idea, but is mostly trying to call politicians blood sucking parasites. This is nothing like drinking bleach as Ivermectin is literally approved for worm removal worldwide. The idea that this would improve overall health and Immunity makes some sense.

[–][deleted] 2 insightful - 1 fun2 insightful - 0 fun3 insightful - 1 fun -  (0 children)

yep it's gross but worms are in almost everyone, we should all take iver once a year, covid or not.