“Psychedelics are illegal, not because a loving government is concerned that you may jump out of a third story window. Psychedelics are illegal because they dissolve opinion structures and culturally laid down models of behaviour and information processing.” ― Terence McKenna

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[–]Jesus 2 insightful - 1 fun2 insightful - 0 fun3 insightful - 1 fun -  (1 child)

I agree, I have delved into psychedelics many, many years ago, before I found God. meditation for long hours or prayer can induce effects very similar to low dose psilocybin and some times dream-like states that feel like one is taken full-blown dosages whilst having a lucid mind. I do not, in any way, negate the fact that they have novel medical purposes and uses that can help an individual, but like everything, one must know what they are doing.

The Kappa-Opioid receptor is what's responsible for Ketamine's disassociation properties. Yes and no. It is also a full blown NMDA antagonist, it doesn't just modulate this receptor like magnesium but blocks it. Ketamine can be psychologically addicting for some, and can cause latent problems in the long run if overused. However, it also has plenty of medically viable properties that can help all kinds of neurodegenerative disorders.

When I see people tell me they are going to try LSD, I laugh because LSD, is rarely ever seen on the street anymore. Rather, these people are takig sythetic derivitives which can and have killed people. Hence this is why, the legaliztion and regulation of psychedelics, like in the Netherlands would be the best answer. It also would be great if more funds were allocated to research their therapeutic properties.

In my personal opinion, all plants have something to teach us.

I agree with you completely.

[–][deleted] 2 insightful - 1 fun2 insightful - 0 fun3 insightful - 1 fun -  (0 children)

It is also a full blown NMDA antagonist, it doesn't just modulate this receptor like magnesium but blocks it.

Yes, that's what I meant by:

"The Kappa-Opioid receptor is what's responsible for Ketamine's disassociation properties, and half of it's anti-depressant effects".

But you are right in this aspect too, glutamate plays an important role as well.

When I see people tell me they are going to try LSD, I laugh because LSD, is rarely ever seen on the street anymore.

Exactly, it's mostly research chemicals. Same with MDMA: I had a friend who was a heroin and just poly drug-addict. I took him to the hospital one time when I had a busy month and he was supposed to be taking a break from heroin, but was binging on MDMA (something you are not supposed to do, ever); he thought he was just taking MDMA - he popped positive for cocaine, meth, something I can't remember as well as MDMA. That's why I personally would only take something with the proper doctor and their proper set-up, but if others feel comfortable doing this solo, that's why testing kits are so important. The cheapest ones will at least let you know your substance isn't what it was advertised as by not lighting up for it. It may pop for multiple things which LSD shouldn't.

Hence this is why, the legaliztion and regulation of psychedelics, like in the Netherlands would be the best answer. It also would be great if more funds were allocated to research their therapeutic properties.

I agree, they are trying to get this set-up in Denver. I've been in contact with them, they have trained trip-sitters who are also doctors and have trip-killing medications available. Anyone can contact them, but they vet your mental health before they accept you for pre-existing conditions outside of things like depression, ptsd or anxiety. They give you the mushrooms for free, but you pay for the trip-sitting (which is reasonable, it lasts pretty much an entire day and is just you, a doctor and a nurse or a family member if you want, they have trip-killing medication in case things don't go well, and will work with you during your trip to make you comfortable and help process traumas, I don't remember what the cost was tbh, but it was under 100 USD). They're literally all experienced doctors, nurses, botanists, neuropsychologists and psychiatrists who grow their own mushrooms and offer safe trip-sitting; I would trust this over buying mushrooms from some random dude off the street and having my friend trip-sit me. It's a first-step in the right direction until we have something more official and better.