Gender dysphoria seems to be a modern mental illness. At the very least it seems internet made it worse and more common.

I think people from the past were too busy working and living on miserable conditions to be able to worry about something so stupid like gender. But idk, it's true gender roles have always existed, and religion has always been obsessed about enforcing them. I imagine that could have caused dysphoria in some people.

I doubt they committed suicide for that or became delusional thinking they could change their sex, though. That's a 21 century problem