Top 5 foods to avoid for gut health by jet199 in HumanMicrobiome

[–]FuckYourMom 2 insightful - 1 fun2 insightful - 0 fun3 insightful - 1 fun -  (0 children)

That guy is an idiot.

Top 5 foods to avoid for gut health by jet199 in HumanMicrobiome

[–][deleted] 2 insightful - 2 fun2 insightful - 1 fun3 insightful - 2 fun -  (0 children)

RIP sprouts. Sprouts did nothing wrong.

Performance-enhancing bacteria found in the microbiomes of elite athletes. Meta-omics analysis of elite athletes identifies a performance-enhancing microbe that functions via lactate metabolism (June 2019) by MaximilianKohlerreads microbiomedigest.com daily in HumanMicrobiome

[–]MaximilianKohlerreads microbiomedigest.com daily[S] 3 insightful - 1 fun3 insightful - 0 fun4 insightful - 1 fun -  (0 children)

Full study: https://sci-hub.tw/https://www.nature.com/articles/s41591-019-0485-4

This is from the Harvard lab trying to make a probiotic from elite athletes.

More useful would be an FMT clinical trial from elite athletes.

Testosterone disruptor effect and gut microbiome perturbation in mice: Early life exposure to doxycycline (Jan 2019) "Early-life exposure to doxycycline shows negative outcomes of testis health in later-life. Early-life exposure to low-dose of doxycycline associates with increased risk of obesity." by MaximilianKohlerreads microbiomedigest.com daily in HumanMicrobiome

[–]Tom_Bombadil 1 insightful - 1 fun1 insightful - 0 fun2 insightful - 1 fun -  (0 children)

Snopes needs advertising dollars too.

Did they debunk the $4 billion dollars paid out in damages?

How about the govts 1% reporting estimate?

Is the corporatists Supreme Court lying, and Snopes is telling the truth?

Does that seem probable??

You have knowledge of the medical Indusrty.... What do you think is more probable?

Edit:. By the way. I am very interested in your feild, and look forward to reading your posts. :-)

Testosterone disruptor effect and gut microbiome perturbation in mice: Early life exposure to doxycycline (Jan 2019) "Early-life exposure to doxycycline shows negative outcomes of testis health in later-life. Early-life exposure to low-dose of doxycycline associates with increased risk of obesity." by MaximilianKohlerreads microbiomedigest.com daily in HumanMicrobiome

[–]Tom_Bombadil 2 insightful - 1 fun2 insightful - 0 fun3 insightful - 1 fun -  (0 children)

I'd like to preface my comments with the fact that I take great interest in this subject matter.
The microbiome will likely be considered the largest organ in the body, and the scientific community is only beginning to scratch the surface of the severely understated and even more underappreciated contrabution of the intestinal microbiome "gut".

Having said that, the indiscriminate destruction that antibiotics wreak on the microbiome is universally understated. This should be obvious to the medical industry, and I find it suspicious that it is not more fully investigated.

Testosterone disruptor effect and gut microbiome perturbation in mice: Early life exposure to doxycycline (Jan 2019) "Early-life exposure to doxycycline shows negative outcomes of testis health in later-life. Early-life exposure to low-dose of doxycycline associates with increased risk of obesity." by MaximilianKohlerreads microbiomedigest.com daily in HumanMicrobiome

[–]Tom_Bombadil 1 insightful - 1 fun1 insightful - 0 fun2 insightful - 1 fun -  (0 children)

It is not a misleading statement.

Well, in the previous link the govt admitted that that estimated that 1% of vaccine injured families reported the injury.

By that account, the actual damages awarded should be closer to $400,000,000,000. Almost half a trillion dollars.

A silent epidemic of unreported damage.

A multi billion dollar industry is keeping the lid on the facts. Most people implicitly trust doctors. It would take overwhelming evidence to change that belief. Half a trillion worth of unrecognized damages would probably have many families outraged.

That is why Facebook and other media are desperately suppressing this information movement.

Big money is spent on advertising in spite of shrinking audiences...

The media is effectively paid off.

Testosterone disruptor effect and gut microbiome perturbation in mice: Early life exposure to doxycycline (Jan 2019) "Early-life exposure to doxycycline shows negative outcomes of testis health in later-life. Early-life exposure to low-dose of doxycycline associates with increased risk of obesity." by MaximilianKohlerreads microbiomedigest.com daily in HumanMicrobiome

[–]MaximilianKohlerreads microbiomedigest.com daily[S] 1 insightful - 1 fun1 insightful - 0 fun2 insightful - 1 fun -  (0 children)

I'm not sure. I'm not knowledgeable enough on that to comment.

But I am very knowledgeable on antibiotics and the microbiome, and to me antibiotics seem like a much bigger threat/harm.

Testosterone disruptor effect and gut microbiome perturbation in mice: Early life exposure to doxycycline (Jan 2019) "Early-life exposure to doxycycline shows negative outcomes of testis health in later-life. Early-life exposure to low-dose of doxycycline associates with increased risk of obesity." by MaximilianKohlerreads microbiomedigest.com daily in HumanMicrobiome

[–]MaximilianKohlerreads microbiomedigest.com daily[S] 1 insightful - 1 fun1 insightful - 0 fun2 insightful - 1 fun -  (0 children)

That's a misleading statement on your part.

You have to look at the rates of vaccine injury vs rates of injury from the diseases the vaccines protect against. You also have to look at the severity of the injuries.

I think the science backing the gut microbiome as the causative factor is the strongest: https://old.reddit.com/r/HumanMicrobiome/wiki/intro#wiki_autism.3A

Though the gut microbiome also impacts vaccine efficacy & immune system: https://old.reddit.com/r/HumanMicrobiome/wiki/immunesystem

Testosterone disruptor effect and gut microbiome perturbation in mice: Early life exposure to doxycycline (Jan 2019) "Early-life exposure to doxycycline shows negative outcomes of testis health in later-life. Early-life exposure to low-dose of doxycycline associates with increased risk of obesity." by MaximilianKohlerreads microbiomedigest.com daily in HumanMicrobiome

[–]Tom_Bombadil 1 insightful - 1 fun1 insightful - 0 fun2 insightful - 1 fun -  (0 children)

Would you also accuse the Supreme Court of making ignorant guesses?

Any possibility that you are misinformed about vaccines?

Testosterone disruptor effect and gut microbiome perturbation in mice: Early life exposure to doxycycline (Jan 2019) "Early-life exposure to doxycycline shows negative outcomes of testis health in later-life. Early-life exposure to low-dose of doxycycline associates with increased risk of obesity." by MaximilianKohlerreads microbiomedigest.com daily in HumanMicrobiome

[–]MaximilianKohlerreads microbiomedigest.com daily[S] 1 insightful - 1 fun1 insightful - 0 fun2 insightful - 1 fun -  (0 children)

You're misinformed about vaccines. You have a tremendous amount of information at your fingertips via a simple web search. Use that instead of making ignorant guesses.

There are some knowledge resources in these comments: https://archive.fo/MpwmK#selection-2331.8-2335.0

Testosterone disruptor effect and gut microbiome perturbation in mice: Early life exposure to doxycycline (Jan 2019) "Early-life exposure to doxycycline shows negative outcomes of testis health in later-life. Early-life exposure to low-dose of doxycycline associates with increased risk of obesity." by MaximilianKohlerreads microbiomedigest.com daily in HumanMicrobiome

[–]Tom_Bombadil 2 insightful - 1 fun2 insightful - 0 fun3 insightful - 1 fun -  (0 children)

It's possible. There are definitely harmful affects associated with antibiotics.

Vaccinations are far worse in my opinion. Newborns receive the hepatitis B vaccine at birth.

I've never known anyone with hepatitis b, so it seems inconceivable to me that a new born would need to immediately receive this. That's just scratching the surface of the vaccine risks.

Testosterone disruptor effect and gut microbiome perturbation in mice: Early life exposure to doxycycline (Jan 2019) "Early-life exposure to doxycycline shows negative outcomes of testis health in later-life. Early-life exposure to low-dose of doxycycline associates with increased risk of obesity." by MaximilianKohlerreads microbiomedigest.com daily in HumanMicrobiome

[–]MaximilianKohlerreads microbiomedigest.com daily[S] 2 insightful - 1 fun2 insightful - 0 fun3 insightful - 1 fun -  (0 children)

Well the "great tool for eugenics" is an antibiotic that is extremely common, and often for trivial things like acne.

In my opinion the situation is quite dire: https://old.reddit.com/r/worldpolitics/comments/a4yeq0/since_there_are_no_rules_here_i_might_as_well_use/

Testosterone disruptor effect and gut microbiome perturbation in mice: Early life exposure to doxycycline (Jan 2019) "Early-life exposure to doxycycline shows negative outcomes of testis health in later-life. Early-life exposure to low-dose of doxycycline associates with increased risk of obesity." by MaximilianKohlerreads microbiomedigest.com daily in HumanMicrobiome

[–]MaximilianKohlerreads microbiomedigest.com daily[S] 2 insightful - 1 fun2 insightful - 0 fun3 insightful - 1 fun -  (0 children)

EDC = endocrine disrupting chemical. https://www.who.int/ceh/risks/cehemerging2/en/

Highlights

• Doxycycline may be EDCs through mitochondrial dysfunction mechanism cause endocrine disruption.

• Early-life exposure to doxycycline shows negative outcomes of testis health in later-life.

• Early-life exposure to low-dose of doxycycline associates with increased risk of obesity.

Abstract

Veterinary tetracyclines drugs are emerging organic pollutants detected at high concentrations in the urine of school children and a potential public health risk. However, the implications of early-life exposure to tetracyclines on testosterone production, being new endocrine disruptors, remain unknown. We investigated whether the early-life exposure to low-doxycycline, a widely used tetracycline, on mitochondria dysfunction and testosterone disruption in Leydig cells in vitro and in vivo. Next, we determined the mRNA levels of testis cells markers for early-life exposure to low-doxycycline outcomes of testis health in later-life. Finally, we compared the weight gain performance exposed to low- and therapeutic-doses through 15 weeks and examined the role of the microbiota during development. Our results showed doxycycline disturbed steroidogenesis process by mitochondrial dysfunction in mouse Leydig tumor cell line (MLTC-1) cells in vitro. Leydig cells mitochondrial function was disrupted by early-life exposure to low-doxycycline from birth to 49 days, causing testosterone deficiency and decreased quality of the sperm in mice. Early-life exposure to low-doxycycline significantly altered the mRNA levels of key genes in Leydig cells (Cyp11a1, Cyp17a1 and 17β-HSD) and spermatogenic cells (Grfal, Plzf, and Stra8) in later-life in mice. Subchronic low- and therapeutic-doses doxycycline changed gut microbiota differences in diversity reduction and compositional alteration. Moreover, the weight gain effects of doxycycline were only observed in low-dose in male mice. Overall, these results provide insight into the effects of doxycycline on both testis and gut microbiota health. The results provide insight that environmental antibiotics are needed additional research to classify as ECDs.

Guide to probiotics. by MaximilianKohlerreads microbiomedigest.com daily in HumanMicrobiome

[–]magnora7 1 insightful - 1 fun1 insightful - 0 fun2 insightful - 1 fun -  (0 children)

Nice, good solution to just make it gray for both

Guide to probiotics. by MaximilianKohlerreads microbiomedigest.com daily in HumanMicrobiome

[–]MaximilianKohlerreads microbiomedigest.com daily[S] 3 insightful - 1 fun3 insightful - 0 fun4 insightful - 1 fun -  (0 children)

Fixed now.

Guide to probiotics. by MaximilianKohlerreads microbiomedigest.com daily in HumanMicrobiome

[–]magnora7 1 insightful - 1 fun1 insightful - 0 fun2 insightful - 1 fun -  (0 children)

Nope unfortunately the text box is still white background with white text in nightmode.

Guide to probiotics. by MaximilianKohlerreads microbiomedigest.com daily in HumanMicrobiome

[–]MaximilianKohlerreads microbiomedigest.com daily[S] 1 insightful - 1 fun1 insightful - 0 fun2 insightful - 1 fun -  (0 children)

Thanks :)

I've been following the microbiome literature very closely, and the wiki here is very extensive as well.

Guide to probiotics. by MaximilianKohlerreads microbiomedigest.com daily in HumanMicrobiome

[–]MaximilianKohlerreads microbiomedigest.com daily[S] 1 insightful - 1 fun1 insightful - 0 fun2 insightful - 1 fun -  (0 children)

I copied over the css from the reddit sub. I've changed that line. Did it fix it?

Gut feeling: study links depression to digestive bacteria by useless_aether in HumanMicrobiome

[–]MaximilianKohlerreads microbiomedigest.com daily[M] [score hidden] stickied comment (0 children)

Someone reported this as spam. I don't think it's spam, but it's better to use sites that directly link to the study, or share the study in the comments.

Guide to probiotics. by MaximilianKohlerreads microbiomedigest.com daily in HumanMicrobiome

[–]magnora7 2 insightful - 1 fun2 insightful - 0 fun3 insightful - 1 fun -  (0 children)

Yeah it's good stuff. I even had a few glasses of chocolate pu'er today! Pretty good.

Guide to probiotics. by MaximilianKohlerreads microbiomedigest.com daily in HumanMicrobiome

[–][deleted] 2 insightful - 1 fun2 insightful - 0 fun3 insightful - 1 fun -  (0 children)

Dude glad to hear this. I knew I was on the right track passive agressively nagging you about kombucha. Glad you found a paletable alternative.

Gut feeling: study links depression to digestive bacteria by useless_aether in HumanMicrobiome

[–]useless_aether[S] 1 insightful - 1 fun1 insightful - 0 fun2 insightful - 1 fun -  (0 children)

hope this wont degenerate into "gut bacteria are bad and must be wiped"

Guide to probiotics. by MaximilianKohlerreads microbiomedigest.com daily in HumanMicrobiome

[–][deleted] 2 insightful - 1 fun2 insightful - 0 fun3 insightful - 1 fun -  (0 children)

commenting to read later

Guide to probiotics. by MaximilianKohlerreads microbiomedigest.com daily in HumanMicrobiome

[–]magnora7 3 insightful - 1 fun3 insightful - 0 fun4 insightful - 1 fun -  (0 children)

I've never considered partial mod permissions before. I don't think that exists. Definitely something we could take a look at, I've added it to our list.

I'm guessing Max just copy/pasted a custom CSS theme from reddit, and that's why this problem came up. Because reddit doesn't have a nightmode and saidit does. Even if he can't do the nightmode textarea background a different color, he could just make both day and night gray with the color #505050 and that should solve the visibility issues. That'd be the easy fix

Guide to probiotics. by MaximilianKohlerreads microbiomedigest.com daily in HumanMicrobiome

[–]wizzwizz4 2 insightful - 1 fun2 insightful - 0 fun3 insightful - 1 fun -  (0 children)

I hate it when my brain tries to autocorrect me when I'm typing.

Yeah, you're right about it being part of the custom CSS. Over on Reddit I've got people to make me a mod to help with CSS issues, but MaximilianKohler's got no reason to believe that I won't mess up this perfectly good sub while I'm at it, so I won't press the issue.

Do we have partial mod permissions here? If not, that's another feature request to add to the list.

Guide to probiotics. by MaximilianKohlerreads microbiomedigest.com daily in HumanMicrobiome

[–]magnora7 2 insightful - 1 fun2 insightful - 0 fun3 insightful - 1 fun -  (0 children)

Ah I figured it out. It's not that the text color changed, but the text box background color changed. It's normally grey, with white text, in night mode. He changed it to be a white background text box. That's this, in the CSS

.commentarea .usertext-edit textarea{ background: #FFFFFF;

should instead be

.commentarea .usertext-edit textarea{ background: #505050;

in night mode. /u/MaximilianKohler you might be interested in this too.

Guide to probiotics. by MaximilianKohlerreads microbiomedigest.com daily in HumanMicrobiome

[–]magnora7 1 insightful - 1 fun1 insightful - 0 fun2 insightful - 1 fun -  (0 children)

Ah very nice catch! I think you mean 'textarea' though, not 'textbox'.

I think it's part of this sub's custom CSS, and not part of the saidit code. So only he can fix it.

Guide to probiotics. by MaximilianKohlerreads microbiomedigest.com daily in HumanMicrobiome

[–]wizzwizz4 3 insightful - 1 fun3 insightful - 0 fun4 insightful - 1 fun -  (0 children)

I came here expecting a "natural health essential oils and magic"-type pseudo-spam post, so I'm absolutely floored by this. This is insightful.

Guide to probiotics. by MaximilianKohlerreads microbiomedigest.com daily in HumanMicrobiome

[–]wizzwizz4 2 insightful - 1 fun2 insightful - 0 fun3 insightful - 1 fun -  (0 children)

It's actually due to the second textbox{ rule in https://saidit.net/static/compiled-css/reddit.z-E2xc4c7EM.css, that explicitly sets color: white;. /u/MaximilianKohler If you want help with the CSS, I'm happy to oblige, but it's difficult to debug the issue without being able to see the unminified version.

Guide to probiotics. by MaximilianKohlerreads microbiomedigest.com daily in HumanMicrobiome

[–]magnora7 2 insightful - 1 fun2 insightful - 0 fun3 insightful - 1 fun -  (0 children)

Hey just a random thing, but I noticed when I view this sub in dark mode, I cannot see the text I type in to the comment text box. I think it has to do with the text overlay that shows before you type anything.

Guide to probiotics. by MaximilianKohlerreads microbiomedigest.com daily in HumanMicrobiome

[–]magnora7 2 insightful - 1 fun2 insightful - 0 fun3 insightful - 1 fun -  (0 children)

I started drinking Pu'er tea, which is a fermented tea that has lots of probiotics. But it's not all foamy like kambucha, it's like regular tea. It has done amazing things for my gut health, especially in combination with green tea.

Guide to probiotics. by MaximilianKohlerreads microbiomedigest.com daily in HumanMicrobiome

[–]MaximilianKohlerreads microbiomedigest.com daily[S,M] [score hidden] stickied comment (0 children)

List of source of strains:

EDIT: here's a project with a list of strains that /u/markus_naslund has started: https://old.reddit.com/r/HumanMicrobiome/comments/aceyab/commercially_available_probiotic_strain_database/

You can PM me for additions so I can keep this updated. If google will not tell you the source you'll have to contact the company and ask. The vast majority are food-sourced so it might be easier to just keep a list of human-sourced.

We have to keep in mind that there is a difference between strains sourced from human stool (which may be transient environmental microbes) and strains sourced from the intestinal wall (which are more likely to be host native). Then we have to keep in mind that not every human-sourced probiotic will be beneficial, or significantly so. Which is why I primarily focus on FMT, and wait till there are proven benefits for new/old strains and simply list the main ones here.

Human-sourced:

Food-sourced:

Unknown source:

Reuteri pearls: https://archive.is/luQNi