And this is why you always wait several months before ever trying any new "medical" anything. Doesn't matter if it's new toothpaste. You still wait 6 months before buying it.

It takes 25 years for half a drug's long term effects to be known. Not sure how factual that is but it's a common rule of thumb. Has to do with it just taking time to realize long term effects from a medication.

You generally don't want to take samples or brand name medication if the generic hasn't been released yet. Those are the guinea pigs.