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[–]LesbianOutlaw 1 insightful - 1 fun1 insightful - 0 fun2 insightful - 1 fun -  (16 children)

A whole cocktail? What is this nonsense? All you need is a single drug to raise prolactin levels — domperidone. It can be used to stimulate milk production in males and females alike. It’s a commonly used drug among females to help them increase their milk production and no one complains, but when a male uses domperidone then it somehow becomes this dangerous hormone cocktail. Just admit that you’re transphobic already and that your views are based on emotions, not logic.

[–]bobbobbybob 4 insightful - 1 fun4 insightful - 0 fun5 insightful - 1 fun -  (14 children)

yeah, show me a study that demonstrates milk production in a male using domperidone that does not require unnaturally high doses.

I guess you are a tranny yourself. 'lesbian outlaw' indeed.

cocktail: https://www.liebertpub.com/doi/10.1089/trgh.2017.0044

The patient obtained domperidone from Canada, an antiemetic used off-label as a galactogogue internationally.7 The patient was started on domperidone 10 mg po tid. The patient also was given instructions to use her breast pump for 5 min per breast TID.

The patient's first follow-up visit occurred at 1 month. On physical examination, she was able to express droplets of milk. The domperidone dose was increased to 20 mg po qid, her micronized progesterone to 200 mg po daily, her estradiol to 8 mg po daily, and her breast pump use to six times daily.

oops. quick, double the dose of D compared to a female, and pump a shit ton more female hormones too.

At the 2nd month visit, her progesterone was increased to 400 mg po daily and her estradiol had increased to 12 mg daily.

hmm. your statement is incorrect. Single drug not enough.

At 6 weeks, the patient began supplementing breastfeedings with 4–8 oz of Similac brand formula daily due to concerns about insufficient milk volume. At the time of this article submission, the baby is approaching 6 months old. The patient continues to breastfeed as a supplement to formula feeding, and she continues to adhere to the medication regimen described earlier.

even with a cocktail of hormones, not enough milk. you will never be a woman.

One major difference between the induction of lactation in cis and transgender women is the need for androgen blockade in the latter group. Our patient continued to take spironolactone while breastfeeding for androgen blockade. A known metabolite of spironolactone, cancrenone is excreted in human milk. This has been shown to be 0.2% of the maternal daily dose, which is thought to be clinically insignificant.16 Spironolactone has been reported to have tumorigenic potential in rats, but according to the American Academy of Pediatrics, it is thought to be compatible with breastfeeding.17

Fancy wanting to play the mum so much that you gaze down at your breastfeeding little one and knowingly expose them to a potentially sex-identification destroying hormone hit.

notice no mention of colostrum production, either. Poor fucking child. At least it has decent weight. It has been 3 years now. where is the follow up paper? That entire paper makes me ill, as do the papers that cite it. At least one of them dares to wonder how good it is for the child. They happily care about the genderbent 'mum's health, but not a single blood sample from the kid to make sure its hormone levels were OK.

[–]LesbianOutlaw 1 insightful - 1 fun1 insightful - 0 fun2 insightful - 1 fun -  (13 children)

Show me a study that demonstrates that milk production in a male using domperidone does require “unnaturally high doses.” You are the one who is making the claim that milk produced by a male taking domperidone is somehow tainted in a way that milk produced by a female taking domperidone isn’t. I don’t believe this matter has been thoroughly researched, but I can tell you from personal experience that I achieved a high level of milk production by using domperidone in the same amounts that it is used when it is prescribed to induce lactation in biological women.

Refer to this article for domperidone dosage information to induce lactation in biological women. I would think the dosages suggested here should be the same for most biological men to induce lactation as well, as it worked fine for me.

[–]bobbobbybob 4 insightful - 1 fun4 insightful - 0 fun5 insightful - 1 fun -  (12 children)

done. see other response.

I achieved a high level of milk production by using domperidone in the same amounts that it is used when it is prescribed to induce lactation in biological women.

Ah, so you are a tranny. Did you have massive doses of spironaolactone, estrogen and progesterone as well? because that's my claim. a cocktail of hormone fucking drugs. How was your first milk? full of collustrum, the immune system fortifying wonder that sets your child up for life, or just milky?

[–]LesbianOutlaw 1 insightful - 1 fun1 insightful - 0 fun2 insightful - 1 fun -  (11 children)

I never took progesterone, and I only take estrogen. My hormone levels are in line with the levels of estrogen you would see in a biological woman. I don’t have to take spironolactone as the estrogen alone is enough to keep my testosterone production suppressed. Why do you keep referring to it as a cocktail anyway? Who takes oral estrogen? It’s garbage. I take injections.

My milk actually was yellowish when I first lactated but it turned white pretty quick. I don’t see why having insufficient colostrum would be an issue however as my wife also shared in the feeding duties for our child. With both partners able to feed the child we were both able to get a good night’s sleep in shifts. I think it’s a much preferable situation to your typical heterosexual, cisgendered couple, where the woman has to do all the work and both parents are tired all the time from having to wake up every couple hours to go feed baby. It’s such a shame that our species evolved in a way where one party has to do all the work. Lactation is an ability present in biological males, but our stupid evolutionary path decided to keep that ability locked away. It requires modern science to fix that evolutionary flaw.

[–]bobbobbybob 4 insightful - 1 fun4 insightful - 0 fun5 insightful - 1 fun -  (5 children)

I take injections.

of what? What exact drug do you get injections of? because as far as i'm aware, you have to have a modified form of estrogen to make up for the lack of continuous gonadal production.

Jesus. You even have a dick and balls still? and you LARPed as mum? Is your baby just an accessory? did you not want to give it the best?

as my wife also shared in the feeding duties for our child

just think you could have just let her do it, and squashed your jealousy.

[–]LesbianOutlaw 1 insightful - 1 fun1 insightful - 0 fun2 insightful - 1 fun -  (4 children)

Estradiol is a bioidentical hormone. Perhaps you should look up what that word means; but then again, scientific facts seem to be of no interest to you.

The only person who seems to be jealous is you. I live my life as I want to without a care for what others think of me, and without trying to conform to arbitrary social standards. I have a happy family and I’m the person I want to be. You on the other hand are hung up on emotions, irrationality, and hatred. That cannot be a very joyful life to live.

[–]bobbobbybob 2 insightful - 1 fun2 insightful - 0 fun3 insightful - 1 fun -  (0 children)

Estradiol is a bioidentical hormone.

lol. forgetting the ad hominem which is going to be your main line of defense going forward, most trannies don't get estradiol, do they, they get estradiol valerate or estradiol cypionate or benzoate etc. Yes, I made a sloppy statement, but let's look at what a tranny can have: https://en.wikipedia.org/wiki/Feminizing_hormone_therapy#Estrogens I did ask you what YOU have but you didn't deign to answer.

As /u/comatoast pointed out, these HRT drugs are contraindicated for breastfeeding women. But you don't give a shit about your baby and are willing to sacrifice them on the altar of self-identity https://www.nature.com/articles/7211251

I live my life as I want to without a care for the long term health of my children

ftfy

[–]bobbobbybob 2 insightful - 1 fun2 insightful - 0 fun3 insightful - 1 fun -  (2 children)

ah. polyestradiol phosphate. Ouch, the pharmacokinetics of that...

You do understand that word, right?

Pharmacokinetics See also: Pharmacokinetics of estradiol PEP has a very long duration and is given by intramuscular injection once every 4 weeks.[35] In men, an initial intramuscular injection of PEP results in a rapid rise in estradiol levels measured at 24 hours followed by a slow and gradual further increase in levels up until at least day 28 (the time of the next injection).[35] Subsequent injections result in a progressive and considerable accumulation in estradiol levels up to at least 6 months.[35] The mean elimination half-life of PEP has been found to be 70 days (10 weeks) with a single 320 mg intramuscular dose of the medication.[7] The tmax (time to maximal concentrations) for estradiol was about 16 days.[7] PEP has a duration of approximately 1 month with a single dose of 40 mg, 2 months with 80 mg, and 4 months with 160 mg.[60][61][62][63][39]

PEP reaches the bloodstream within hours after an injection (90% after 24 hours), where it circulates, and is accumulated in the reticuloendothelial system.[52] Estradiol is then cleaved from the polymer by phosphatases, although very slowly.[64] Levels of estradiol in men with intramuscular injections of PEP once every 4 weeks were about 350 pg/mL with 160 mg, 450 pg/mL with 240 mg, and almost 700 pg/mL with 320 mg, all measured after 6 months of treatment.[35] With monthly injections, steady-state estradiol concentrations are reached after 6 to 12 months.[52] Estradiol is metabolized primarily in the liver by CYP3A4 and other cytochrome P450 enzymes, and is metabolized to a lesser extent in extrahepatic tissues.[20][1] The metabolites are mainly excreted in urine via the kidneys.[1]

Early studies found that a dosage of 80 mg PEP every 4 weeks rapidly produced relatively high mean estradiol levels of about 400 to 800 pg/mL.[65] These levels are similar to those of 100 mg estradiol undecylate every month, which has been found to produce estradiol levels of around 500 to 600 pg/mL.[66][67] As a result, it has previously been said that 80 mg PEP per month and 100 mg estradiol undecylate per month are roughly equivalent.[68][69][7] However, subsequent studies showed that this dosage of PEP actually achieves much lower estradiol levels than originally demonstrated.[35]

source: https://en.wikipedia.org/wiki/Polyestradiol_phosphate#:~:text=The%20mean%20elimination%20half%2Dlife,estradiol%20was%20about%2016%20days.

hmm. nice for the bubs. that good long term build up of female sex hormones with a half life 100x times that of the 17h of estradiol itself. must be why its use is contraindicated in..... breastfeeding

[–]Questionable 1 insightful - 2 fun1 insightful - 1 fun2 insightful - 2 fun -  (1 child)

Well this was a rather nauseating thread to have to read through.

[–]C3P0 3 insightful - 1 fun3 insightful - 0 fun4 insightful - 1 fun -  (0 children)

Right. I get really confused when reading trans articles because I never know if she means he. Then I am lost and don't know who they are talking about.

[–]bobbobbybob 1 insightful - 1 fun1 insightful - 0 fun2 insightful - 1 fun -  (4 children)

My milk actually was yellowish when I first lactated

Lies come easy, once your whole identity is a lie

[–]FediNetizen 2 insightful - 1 fun2 insightful - 0 fun3 insightful - 1 fun -  (2 children)

Are you familiar with autogynephilia? It's really interesting, and understanding what drives autogynephiles will help you understand people like this. I can recommend this Quillette interview with the guy who coined the term for starters.

[–]bobbobbybob 2 insightful - 2 fun2 insightful - 1 fun3 insightful - 2 fun -  (1 child)

yes, I first met the term when i hit peak trans, and learnt to spot the autogyne smile. I bet tranny mode thinks its alluring when he sees it in the mirror

[–]FediNetizen 2 insightful - 1 fun2 insightful - 0 fun3 insightful - 1 fun -  (0 children)

Trannys looking like a bag of smashed ass yet still enjoying looking at their reflection is creepy, but not nearly as creepy as a breastfeeding fetish. This guy went from "I'm a true and honest woman, I don't know why you would think otherwise" to "yeah, I take meds to induce lactation so I can enjoy having my kid suck on my moob, what's the problem transphobe?".

[–]copenseethe 2 insightful - 1 fun2 insightful - 0 fun3 insightful - 1 fun -  (0 children)

Your views seem to be influenced by your sexual fetish.