Is sex determined by chromosomes or phenotype? Are people with CAIS male or female? Doesn't CAIS challenge binary sex?

submitted by IWoreWhat from (self.GenderCriticalGuys)

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[–]IWoreWhat[S] 1 insightful - 1 fun1 insightful - 0 fun2 insightful - 1 fun -  (1 child)

I apologize, but that was not helpful at all. And this one here:

What determines sex, phenotype or chromosomes? Yes.

Sounds like a "how many x do you want? Yes" meme. Not an actual answer.

How are XX males without SRY males? Depends on the individual symptoms of the condition.

Please explain how, according to those symptoms of conditions.

What is their sex? Female.

Why?

[–]QuondamPhysics 1 insightful - 1 fun1 insightful - 0 fun2 insightful - 1 fun -  (0 children)

"Yes" is so an actual answer. Both phenotype and chromosomes contribute to the sex of the individual.

As to how XX males without SRY are in fact males, as I said, that depends on how the individual body develops as a result of the disorder. Consulting Wikipedia on the subject, I find that XX males are born with smaller or deformed secondary sex characteristics, many have decreased body hair or gynecomastia, some have decreased libido. All are sterile. However what I'm reading is that each individual develops as a result of their condition differently. As Wiki states, "the degree to which individuals with XX male syndrome develop the male phenotype is variable, even among SRY-positive individuals." Some may develop with an over-abundance of female characteristics. Some may have more male characteristics. An XX male without SRY may develop as a male due to factors we haven't considered or don't understand. It's a matter between the patient and his or her doctor. Arguably they don't have a sex at all.

Short answer: I'd need an M.D. in endocrinology to give that question the consideration it deserves.

As to your apology, no worries! This sub could use more content. :)

EDIT: Q: What is their sex? A: Female. Q: Why? A: Female phenotype. Just because we have 99.3% chimp chromosomes doesn't make us a chimp.

EDIT EDIT: It also depends on how the biological system expresses these genes and how the different organ systems interact with each other. Chromosomes aren't necessarily the blueprint for making a person, they're more like a rough sketch with tons of preliminary artwork. Ultimately the body that is created is the result of the plans being changed on the fly as the result of external conditions. While I'm aware that such an analogy could easily be used as some patchwork justification for the concept of 'gender identity', that entire line of thinking is based on a false premise, that gender identity is based on some sort of biological justification rather than a purely social phenomenon.

I'm legit sorry I can't be more helpful to you. For them to demand complex medical diagnoses regarding endocrinological disorders from laypeople isn't a reasonable position.