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[–]magnora7[S] 3 insightful - 1 funny3 insightful - 0 funny4 insightful - 1 funny -  (2 children)

Could this type of finding be related to the high autism rate I posted about today?

How many now-common medications (and other chemicals we come in to contact with as modern humans) have very serious common side effects that take decades to manifest?

[–]DoKtor 3 insightful - 1 funny3 insightful - 0 funny4 insightful - 1 funny -  (1 child)

I hope to god the british aren't using tricyclic antidepressants casually. they are the literal most dangerous antidepressant in existance - the kind where if you OD your heart stops and you die.

I'm not sure if this is the chicken or the egg here. Depression in itself can be a prodrome for dementia, and there is already a correlation between the two. Not to mention that a cardinal feature of advanced Parkinsons disease is dementia.

In my personal experience, british medical journals like BMJ funded by their NIH are sketchy when it comes to reliability. They tend to push studies that are anti-interventionist and I have concerns that this is to save money for their great socialist utopia. For example: They touted an article with conclusions that per cutaneous coronary interventions (intravascular procedures to remove clots causing heart attacks) did not improve long term survival in certain types of heart attacks, and went so far as to suggest we do not intervene on these types of heart attacks, which means that we should let the tissue die -> which decreases heart function and puts you at risk of life threatening arrhythmias. - Messed up IMO

Something that isn't british that is concerning is the use of Proton Pump inhibitors. These are also linked to dementia. The shitty thing here is that proton pump inhibitors can help prevent esophageal cancer in people with chronic acid reflux and Barrett's esophagus. My assumption is that most people would rather die older of dementia than die younger of esophageal cancer.

https://jamanetwork.com/journals/jamaneurology/fullarticle/2487379?utm_campaign=articlePDF&utm_medium=articlePDFlink&utm_source=articlePDF&utm_content=jamaneurol.2015.4791

Every drug has the potential to have an insane amount of side effects, the human body is super complex and we still do not know the biochemistry well. We have about 2 billion years of evolution to catch up on.

[–]i_cansmellthat 1 insightful - 1 funny1 insightful - 0 funny2 insightful - 1 funny -  (0 children)

Scary thing about proton pump inhibitors is that a very large portion of the population takes them on a regular basis. Don't have stats, but I take a lot of medical histories and from what I have personally encountered people are more likely to be on them than not.