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It seems Wiktionary still keeps the original definition: https://en.wiktionary.org/wiki/vaccine

vaccine (countable and uncountable, plural vaccines)

(immunology) A substance given to stimulate the body's production of antibodies and provide immunity against a disease without causing the disease itself in the treatment, prepared from the agent that causes the disease (or a related, also effective, but safer disease), or a synthetic substitute. The process of vaccination. My dog has had two vaccines this year.