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[–]Maniak🥃😾[S] 3 insightful - 2 fun3 insightful - 1 fun4 insightful - 2 fun -  (0 children)

Highlights

  • Drug repositioning is a useful and effective idea for Covid-19 antiviral discovery.

  • Ivermectin has proven effective for HIV-1, Adenovirus, Influenza virus, SARS-CoV, and many more, in the past.

  • Due to genomic similarity between SARS-CoV-2 and the SARS-CoV, the role of the IMPα/β1 complex for viral protein (NSP12-RdRp) shuttling between the nucleus and cytoplasm holds great potential.

  • Ivermectin also exhibits great potential in reducing SARS-CoV-2 viral replication via numerous modes of action, such as the disruption of the Importin heterodimer complex (IMPα/β1).