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FDA: It's not that the new booster jabs aren't more effective, just the studies weren't big enough to work right. Also FDA: we recommend you take boooosters on the basis of a study that used only 8 rats.
submitted 1 year ago by iamonlyoneman from cnbc.com
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[–]iamonlyoneman[S] 1 insightful - 1 fun1 insightful - 0 fun2 insightful - 0 fun2 insightful - 1 fun - 1 year ago* (0 children)
Interesting commentary: https://www.rintrah.nl/now-they-discover-they-fucked-up/
Congratulations, now you see the problem. There’s no increased T cell recruitment following the bivalent booster versus the original booster. You can’t meaningfully adjust the response to new variants anymore.
There’s no way to spin these results as suggesting anything other than a very nasty strong original antigenic sin mechanism that’s now making it impossible to adjust people’s immune response to novel variants of this virus. The body can no longer learn new tricks, it just deploys the same old tricks the virus is evolving to overcome. . . . Not just is the booster completely mismatched for the variants that are now going to circulate. No my friends, it’s worse than that. The booster can’t even induce a proper immune response against the variant it contains. . . . Then with BQ.1.1 and the others now emerging, you see variants that avoid (almost) all neutralizing antibodies.
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[–]iamonlyoneman[S] 1 insightful - 1 fun1 insightful - 0 fun2 insightful - 0 fun2 insightful - 1 fun - (0 children)