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[–]send_nasty_stuff 2 insightful - 2 fun2 insightful - 1 fun3 insightful - 2 fun -  (4 children)

I've heard pine tinctures can increase test and reduce estrogen.

[–]infocom6502 1 insightful - 1 fun1 insightful - 0 fun2 insightful - 1 fun -  (3 children)

That would be nice.

This gets me interested in this suramin. wiki says not orally bioavailable. It's a pretty big molecule. But perhaps its fragments are absorbed by intestines. It is slowly broken down by kidneys:

Suramin is not orally bioavailable and must be given intravenously. Intramuscular and subcutaneous administration could result in local tissue inflammation or necrosis. Suramin is approximately 99-98% protein bound in the serum and has a half-life of 41–78 days average of 50 days; however, the pharmacokinetics of suramin can vary substantially between individual patients. Suramin does not distribute well into cerebral spinal fluid and its concentration in the tissues is equivalently lower than its concentration in the plasma. Suramin is not extensively metabolized and about 80% is eliminated via the kidneys

Suramin is not orally bioavailable and must be given intravenously. Intramuscular and subcutaneous administration could result in local tissue inflammation or necrosis. Suramin is approximately 99-98% protein bound in the serum and has a half-life of 41–78 days average of 50 days; however, the pharmacokinetics of suramin can vary substantially between individual patients. Suramin does not distribute well into cerebral spinal fluid and its concentration in the tissues is equivalently lower than its concentration in the plasma. Suramin is not extensively metabolized and about 80% is eliminated via the kidneys

[–]send_nasty_stuff 1 insightful - 1 fun1 insightful - 0 fun2 insightful - 1 fun -  (2 children)

Joe and Andrew talked about two substances I'd never heard of in this segment. Have you heard of them?

https://www.youtube.com/watch?v=bJWmJo3w_0Y

[–]infocom6502 1 insightful - 1 fun1 insightful - 0 fun2 insightful - 1 fun -  (1 child)

Plants can definitely be effective medicines. It's possible that these may be plant hormones that can also have effects on the human system. Others are alkaloids that often also have all sorts of effects.

[–]send_nasty_stuff 2 insightful - 1 fun2 insightful - 0 fun3 insightful - 1 fun -  (0 children)

Suramin seems to have a lot of side effects.