It's the pinnacle of po-mo thought. It's the idea that you are not your body, you are merely your brain, and your body is a prison to escape from. Making peace with it is impossible. Your only recourse is to destroy it as an act of protest, either through drugs or food or plastic surgery, until you can no longer recognize it. Your poison is just whatever you like the most.

Of course then reality catches up, and these people are trapped in mutilated shells. Recognizing the mistake would be too great a blow to the ego, so society has to validate them instead. Of course it's only a temporary fix. You cannot escape your body.