These people make the claim that having a vagina,xx,different body and bone structures don't make someone a woman.If none of that makes someone a woman then we should then ask them what makes a trans woman a "woman".If they bring up the brain argument,link them to this article.(NOTE,this article is pro trans but admits that the brain argument is outdated) https://blogs.scientificamerican.com/voices/stop-using-phony-science-to-justify-transphobia/
From the article,
"There is no such thing as “the male brain” or “the female brain.” This is not to say that there are no observable differences.Certain brain characteristics can be sexually dimorphic: observable average differences across males and females. But like biological sex, pointing to “brain sex” as the explanation for these differences is wrong and hinders scientific research."The article did try to claim trans brains were similar to the gender they identify with,but isn't that contradicting itself?They can't say there's no male/female brain but then try to point out similarities between trans women and biological women brains to prove they're really women.
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