Be careful, because i intended to post this as a warning.

It is also an illness and can be very deadly and severe. Especially when you combine uppers and downers you can be dead faster from combining drugs than your head can hit the the ground.

Politoxicomania for a even a short period almost always induces severe mental problems after the physical problems wear off. If they even do ever. Honestly i never met anyone abusing multiple substance without mental problems in the footsteps of these actions.

Above that are the combinations: The hardest one i saw myself so far in another human was Politoxicomania and Borderline Personality disorder both in extreme intensity.

I felt really sorry for that girl because she already accepted the fact that she will die very young. I think she was hit harder by these illnesses than any other human being that i ever met so far. She is one of the reasons i really try to get behind how to heal the human heart that is located in your head.

Using too many https://en.wikipedia.org/wiki/Hallucinogen s can also severely damage your mind so don't underestimate any one of them.