The dogma is "U=U". I can't comment on whether this is a trustworthy statement as HIV virology is not my expertise. But, HIV aside, it's clear that random unprotected sex is a great way to spread all kinds of diseases including those we don't know about yet and those that we are just learning about (MPX). When I began to understand how people were using PrEP, I predicted that another health crisis would emerge, and MPX did not disappoint. On the one hand you would hope that MPX, being relatively benign in the grand scheme, would serve as a lesson and teach promiscuous gay men to keep their pants zipped up. But I'm old enough and black-pilled enough to know better.