It is (controversially) estimated that when the mother of emperor Constantine convinced her son to make her ('Christian') cult into the official Religion of the Roman Empire(!), this resulted in a set of events that would set civilization back at least one thousand years ... a whole fucking millennium!

Hellenism ended and is sometimes (also controversially) estimated (Wikipedia notwithstanding) to have ended with the murder of Hypatia by a Christian mob. This was a woman(!) scholar, scientist and philosopher and the head of the Platonic School of Alexandria. And she was gruesomely murdered by an imbecilic superstitious mob for being ... 'a witch'!

A religion with dark primitive tribal elements would slowly become law in the Roman Empire, ... making people more and more superstitious and dogmatic ... thus stopping short previous advancements in philosophy/science.

And such people would of course view with fear the technological marvels of Hellenism, like the Antikythera Mechanism, considering them magical and devilish and wanting to destroy them ... as they did so many statues and more ... which is why, though the Antikythera Mechanism was mass-produced, only this one badly corroded example survived, which was saved, ironically enough, by a shipwreck!