You can ingest any drug and they will still have the same physiological effects. You'll still get a vasoconstricted walnut potdunker and dilated pupils and look like a sweat-sodden alien if you took MDMA but there will be zero change in brain chemistry, so serotoninergic and dopaminergic reuptake inhibitors are virtually inoperable with substances. You'll be like a base human android that can only attain gratification from natural responses, like a weirdo. You can still drink tea but it'll need to be low enough in caffeine so as to constitute a super weak cuppa.

You can still use all of the same platforms but music will be muted wherever there is music. At least you get the small pleasure of bobbing those dogshit wobble crank intros on most tutorial vids.